Isolated hypothermic perfusion of the liver.

The technique of hypothermic perfusion.

The machine described is in commercial production although the perfusions, to date, were performed with the prototype described by Ross (1960a). The extracorporeal circuit is mounted on the front of the machine (Fig. 1) under the vision of the perfusionist and comprises: Coronary suction reservoir (A) into which all wound and coronary sinus blood is returned by suction from a horizontally mount...

The Groningen Hypothermic Liver Perfusion Pump: Functional Evaluation of a New Machine Perfusion System

Isolated, Hypothermic Cardioplegia Using Aortic Root Perfusion: A Technical Description

Management of the coronary circulation during cardiopulmonary bypass has remained a controversial issue for many years. A variety of perfusion techniques have been developed to protect the myocardium from ischemia and at the same time provide easy access to pathologic lesions requiring surgical intervention. Included in these techniques are total body hypothermia, normothermic ischemic arrest, ...

The Groningen Hypothermic Liver Perfusion Pump: Functional Evaluation of a New Machine Perfusion System

Liver preservation by single passage hypothermic "squirt" perfusion.

A single passage, hypothermic, intermittent squirt perfusion of the pig's liver is described which has allowed preservation of porcine livers for up to 17 hours. After preservation, orthotopically allografted livers can maintain recipient animals in good health. If this technique can be applied to clinical liver transplantation it should be possible to move livers from one hospital to another i...